Nephroprotective and curative effects ofFicus religiosalatex extract against cisplatin-induced acute renal failure

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Protective Effects of Crocin against Cisplatin-Induced Acute Renal Failure and Oxidative Stress in Rats

Background. The major side effect of cisplatin, used in some tumours, is nephrotoxicity. Reactive oxygen species and oxidative damage are the most important factors in cisplatin-induced acute renal failure. The main purpose of this study is to investigate the protective effects of crocin against cisplatin-induced acute renal failure and oxidative stress in rat. Methods. In this study, animal...

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protective effects of crocin against cisplatin-induced acute renal failure and oxidative stress in rats

background. the major side effect of cisplatin, used in some tumours, is nephrotoxicity. reactive oxygen species and oxidative damage are the most important factors in cisplatin-induced acute renal failure. the main purpose of this study is to investigate the protective effects of crocin against cisplatin-induced acute renal failure and oxidative stress in rat. methods. in this study, animals w...

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Nephroprotective Effect of POLYCAN on Acute Renal Failure Induced by Cisplatin in Rats

We performed to evaluate the effect of POLYCAN (β-glucan) on cisplatin-(CDDP-)induced acute renal failure (ARF) in rats. POLYCAN was administered orally once a day for 32 days. Each of 8 rats per group was selected based on the body weight (BW) after acclimatization and they were sacrificed at 5 days after CDDP injection. There was significant (P < 0.05) increase of BW after CDDP dosing in all ...

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Protective effects of crocin against cisplatin-induced acute renal failure and oxidative stress in rats.

BACKGROUND The major side effect of cisplatin, used in some tumours, is nephrotoxicity. Reactive oxygen species and oxidative damage are the most important factors in cisplatin-induced acute renal failure. The main purpose of this study is to investigate the protective effects of crocin against cisplatin-induced acute renal failure and oxidative stress in rat. METHODS In this study, animals w...

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Nephroprotective Effects of Saponins from Leaves of Panax quinquefolius against Cisplatin-Induced Acute Kidney Injury

Although cisplatin is an anticancer drug that has activity against malignant tumor, it often causes nephrotoxicity. Previous reports have confirmed that the saponins from the leaves of P. quinquefolium (PQS) exerted many pharmacological activities. However, the renoprotective effects of PQS were still unknown. The purpose of the present research was to discuss renoprotective effect of PQS in a ...

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ژورنال

عنوان ژورنال: Pharmaceutical Biology

سال: 2013

ISSN: 1388-0209,1744-5116

DOI: 10.3109/13880209.2013.793718